Almost 95% of the world's population is carriers of the herpes virus. Under unfavorable conditions, it is activated and manifests itself on the skin and mucous membranes. Since the virus is very resistant, special potent antiviral drugs are used to treat it.
What is herpes
Herpes is an intracellular virus that is able to integrate into the genetic apparatus of a cell and start multiplying there. It manifests itself in the form of a bubble rash on the genitals, lips. The rashes burst and turn into wounds, which can coalesce and form a weeping spot covered with a crust. The wounds are soaked, itchy, and do not heal until the herpes virus multiplies in the body.
A bacterial infection can join the wound, plus fluid and is a source of infection.
Herpes is activated if the protective properties of the body weaken, for example, after hypothermia.
Rashes are only an external manifestation of infection. Most frightening of all, the herpes virus is capable of infecting nerve fibers and their plexuses (ganglia). If the disease has managed to spread through the nervous system, even after the most powerful treatment, the virus will remain there forever. The acute stage of the disease can fade away under the influence of correctly selected therapy, but a person will forever remain a carrier and source of infection.
If the virus is in an active state, then it is able to inhibit the production of interferons in the human body. This is what leads to a decrease in immune forces against the background of an exacerbation of herpes.
There are several types of transmission of the pathogen:
- contact-household (it includes the genital tract, if the herpes virus has infected the mucous membranes of the external genital organs. And also transmission through household items, kisses);
- airborne (typical for chickenpox);
- transmissible (infection through microtrauma, cuts, wounds, during medical procedures and blood transfusion).
If left untreated, the herpes virus can be very dangerous. For example, in pregnant women, it can provoke miscarriages, fetal deformities, severe brain damage to the unborn child.
Herpes virus treatment
There are several antiviral drugs that can suppress the herpes virus. Very often doctors prescribe "Alpizarin". The drug is available in the form of tablets and ointments. The active ingredient that Alpizarin contains is tetrahydroxyglucopyranosylxanthene. It is isolated from alpine penny grass and mango leaves.
"Alpizarin" has several actions on the body:
- immunostimulating (able to induce the production of interferon gamma in blood cells).
"Alpizarin" has a moderate anti-inflammatory effect.
Tetrahydroxyglucopyranosylxanthene is active against DNA-containing viruses, is able to suppress their reproduction at early stages of development, but does not affect the activity of viral neuraminidase. The viruses of smallpox, herpes simplex, cytomegalovirus, chickenpox and shingles are sensitive to this substance.
Alpizarin is most effective in the early stages of the disease. It is very quickly absorbed from the gastrointestinal tract and enters the bloodstream, where its constant concentration is kept for 5 hours after taking the pill.
Doctors prescribe "Alpizarin" for:
- acute and recurrent infections caused by the herpes simplex virus, of various localizations (including on the genitals);
- viral diseases of the oral mucosa (aphthous stomatitis);
- Kaposi's herpetiform eczema;
- cytomegalovirus infection;
Alpizarin tablets are prescribed for adults and children over 3 years old.Children from 3 to 6 years old need to take 0.5-1 tablet 2-3 times a day, children 6-12 years old - 1 tablet 2-3 times a day, adults and children over 12 years old - 1-2 tablets 3-4 times a day. The duration of the course will directly depend on the severity of the disease and its form.
If the herpes virus is of genital or extragenital localization, then the course will be 5-14 days. With herpetiphoric Kaposi's eczema and cytomegalovirus infection - 7-21 days. With aphthous stomatitis, patients are treated for 5-15 days, with shingles and chickenpox - 5-21 days.
If a relapse occurs, the doctor prescribes a repeated course of "Alpizarin". For prevention, it must be taken one month after the main course, its duration will be 10-14 days.
Alpizarin ointment can be used by adults and children from 1 year old. Apply it to the skin 4-6 times a day. Doctors prescribe 5% ointment for adults, and 2% for children. For application to mucous membranes, "Alpizarin" is prescribed in the form of a 2% ointment.
It is recommended to carry out simultaneous treatment with tablets and ointment, this significantly reduces the risk of infection, weakens the virus and helps the skin and mucous membranes to recover faster.
Contraindications and side effects during treatment with "Alpizarin"
There are very few side effects while taking the drug, basically they all boil down to allergic reactions, in addition there may be nausea, vomiting, diarrhea, headache, and increased fatigue.
"Alpizarin" is prohibited for pregnant women, breastfeeding women, people with hypersensitivity to the components of the drug. The drug is strictly prescription, so taking it yourself is highly discouraged.
Most of the patients who have used the drug "Alpizarin" leave very positive reviews about it. It is noted that it is especially effective in the treatment of diseases caused by the herpes simplex virus. In addition, the product is very affordable: Alpizarin tablets cost an average of 180 rubles per 20 pieces in pharmacies, and an ointment costs 85 rubles per 10 g.
Analogues of "Alpizarina"
For the treatment of the herpes simplex virus, there are several more effective and proven remedies that doctors like to prescribe. As an external therapy for treatment, it is worth trying to use an ointment containing acyclovir. In pharmacies, you can find many manufacturers who produce it.
Acyclovir is a substance that has antiviral effects. The drug is incorporated into the viral DNA chain and blocks its synthesis by competitive inhibition of viral DNA polymerase. Acyclovir is very specific and acts mainly on the herpes simplex virus, varicella-zoster virus and herpes zoster, moderately active against cytomegalovirus.
With herpes, acyclovir is able to prevent the formation of new elements of the rash, reduces the likelihood of spreading on the skin and complications to internal organs and systems. When taking the medication, the formation of crusts increases, the pain decreases (when the herpes virus affects the cells of the nervous system).
Ointment containing acyclovir can be used to treat external manifestations of the herpes virus only in adult patients who have reached the age of 18. This is a significant drawback of the drug. The duration of treatment should not exceed 10 days.
Since the agent is external, when applied, itching, hyperemia, dryness, peeling, burning, inflammation may occur when it comes into contact with delicate mucous membranes. It is also possible that allergic dermatitis occurs, which leads to thinning of the skin.
There are also tablets that contain acyclovir. They are used in combination therapy, in combination with external agents.
Acyclovir, when taken for a long time and constantly, has a negative effect on many organ systems, therefore, treatment must be carried out strictly under the supervision of a specialist.