What Is Glucose Intolerance

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What Is Glucose Intolerance
What Is Glucose Intolerance

Video: What Is Glucose Intolerance

Video: Glucose Intolerance 2022, November
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Glucose and galactose intolerance is relatively rare - in one case out of 30-60 thousand. It manifests itself already in a newborn baby, manifests itself in the form of watery diarrhea, pain and distention of the intestines, profuse gas formation. If you do not transfer the baby to a special diet in time, the work of the kidneys and liver may be disrupted, cataracts and developmental delays will appear.

Glucose intolerance
Glucose intolerance

Instructions

Step 1

Glucose intolerance is an inherited disorder where there is a lack of enzymes to convert galactose into glucose. Mother's milk contains a lot of lactose, which, with the help of enzymes, is broken down to glucose and galactose, so such food for sick children is very dangerous. You can find out about the presence of primary malabsorption syndrome already in the first days of a child's life with the help of screening.

Step 2

There are three types of congenital glucose intolerance. The first manifests itself within a few days or even weeks after birth. Jaundice begins, appetite decreases, vomiting and diarrhea often appear. Characterized by hepatomegaly and stunting, drowsiness and septicemia, in severe cases, coma, acidosis, anemia. Children need the right one, without lactose and glucose, special mixtures are prescribed. If galactosemia is not treated, the child will lag behind in development and growth, often delayed development of speech and cognitive functions, cataracts.

Step 3

The second type is called "Duarte", while the symptoms are not so pronounced, cataract develops, intracranial hypertension. Patients are allowed to stay on a normal course, the course of the disease is usually benign. The third type is the least common, which is similar to the classic course of the disease, sometimes it can be accompanied by deafness.

Step 4

The mechanism of action of enzymes is as follows. The body receives lactose in the form of milk sugar. It should turn into glucose, but with galactosemia, the amount of enzymes in the liver is reduced. As a result, the content of glucose-1-phosphate in erythrocytes rises, the blood cannot carry the required amount of oxygen, its transport decreases 20-30 times, and the tissues become "oxygen starved". All this leads to disruptions in the development and growth of children.

Step 5

Galactose metabolites accumulate in the kidneys, blood, brain, lens of the eye, heart, damage organs and disrupt the functioning of the system. In the lens of the eye, this leads to cataracts, in the liver - to cirrhosis, in the brain - to delayed speech development, in the liver - to hypoglycemia, in the intestine - to a decrease in the transport of amino acids, etc.

Step 6

If the treatment was started on time, the child was immediately transferred to artificial nutrition without lactose, complications can be avoided. Most often, a strict patient safely survives to adulthood. The longer the treatment is delayed, the more difficult it is to stop the progression of the disease, there is no need to talk about a complete cure.

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