Antiallergic drug Cetirizine blocks H1-histamine receptors, preventing the development or weakening hypersensitivity reactions. Subject to the rules of use, the drug practically does not have sedative and anticholinergic effects, the therapeutic effect lasts for 3 days after administration.
Composition and form of release
Cetirizine is presented in pharmacies in various dosage forms: tablets, drops, syrup. The drug can be purchased without a prescription. The active component of the drug is cetirizine hydrochloride, the concentration of which in 1 tablet is 10 mg, in 1 ml of drops - 10 mg and 1 ml of syrup -1 mg.
The drug effectively prevents the development of allergies, affecting the early stage of its formation, and also suppresses the release of inflammatory mediators at a later stage. As a result, manifestations of hypersensitivity are eliminated or weakened, the drug reduces vascular permeability, swelling, relieves spasm of smooth muscles, has antipruritic, antiexudative effects. The therapeutic result is noted 1 hour after the application of the agent.
Taking the drug is indicated for:
- allergic rhinitis and conjunctivitis;
- dermatoses with characteristic itching;
- hay fever;
A course of treatment
The rules for using Cetirizine depend on the dosage form.
Adults and children over 12 years old are shown the use of 1 tablet, 10 ml of syrup or 20 drops of the drug. A child of 6-12 years old is prescribed 5 mg (1/2 tablet) with a weight of less than 30 kg or 10 mg (1 tablet) with a body weight of over 30 kg. The syrup is allowed to be taken from 2 years old, 5 ml with a weight of up to 30 kg or 10 ml with a weight of more than 30 kg. Drops are prescribed from 1-2 years old at a dose of 5 drops twice a day, at the age of 6-12 years, 10 drops twice a day or 20 drops once.
It is preferable to take it in the evening, regardless of food intake.
The dose and regimen of administration is recommended to be agreed with the doctor taking into account chronic diseases (renal and liver dysfunctions) in order to avoid the development of complications.
The drug is well tolerated and rarely accompanied by negative effects. It practically does not have a sedative and anticholinergic effect, unlike many drugs in this group.
Side effects include:
- intolerance to the constituents of the remedy;
- manifestations of dyspepsia;
- headache, fatigue, dizziness.
Usually, these symptoms are temporary and go away on their own.
Cetirizine is prohibited to use when:
- severe kidney pathologies;
- pregnancy and lactation;
- intolerance to the constituents of the remedy.
During the period of treatment, it is not recommended to take alcohol in order to avoid depression of the central nervous system. It is advisable to abandon activities that require increased concentration of attention and reactions.
Analogs and prices
Analogues of Cetirizine include antihistamines:
- Fexofenadine and others.
The price of the drug depends on the dosage and dosage form: the average cost of a package of 20 tablets of 10 mg each is 80-90 rubles, a drop in a 20 ml bottle (10 mg / ml) is 226 rubles.