For normal functioning, the human body needs a set of vitamins and minerals. One of the vital vitamins is vitamin A. In the dosage form, it is presented as retinol acetate.
Types and pharmacological action
Retinol acetate is available in the form of an oil solution and a drop for external and internal use, ampoules for intramuscular injections, tablets and capsules for oral administration. The most effective in the use of ampoules for injection with retinol, while tablets and capsules, passing through the stomach, lose some of their healing properties. In the pharmaceutical industry, vitamin A is most often combined with tocopherol (vitamin E).
Being a fat-soluble vitamin, retinol takes an active part in the metabolism and redox processes of the body, enhances the production of lipase, an enzyme responsible for the digestion and dissolution of fats, and regulates the production of myeloid cells in the bone marrow that support immunity.
Retinol has a beneficial effect on the visual receptors, as well as the healthy condition of the skin, hair, nails and mucous membranes, effectively fights premature wrinkles. The positive effect of retinol in the fight against cancer cells of some types of tumors has been proven.
Once in the body, retinol acetate reaches its maximum concentration in the blood serum within three hours after ingestion. With intramuscular injection, the time is halved.
Indications and methods of application
Indications for the use of retinol acetate are a lack of vitamin A (hypoavitaminosis), frequent and prolonged colds, various eye diseases (decreased visual acuity, dryness of the conjunctiva of the eye, destruction of the retinal epithelium, etc.), excessive dryness, tightness and purulent-septic and allergic skin lesions (seborrheic dermatitis, acne, eczema).
During pregnancy, retinol acetate is used to prevent stretch marks and improve the general condition of the mother and baby. Retinol acetate is also used for gastrointestinal disorders (diarrhea, rehabilitation after gastrectomy, irritable bowel syndrome).
Absolute contraindications for use are: 1 trimester of pregnancy, an excess of vitamin A, heart failure, chronic kidney and biliary tract diseases, obesity of 2 and 3 degrees.
The dosage of the drug should be prescribed by the attending physician; self-medication should not be performed. For prophylactic purposes, retinol acetate is prescribed in the amount of 33,000 IU, this is one capsule, in the morning 15-20 minutes after breakfast, or 2 tablespoons of the solution per 100 ml of water in the morning on an empty stomach.
For cosmetic purposes 1 tbsp. the oil solution is added to various masks, or 3-4 drops are applied to the face at night to moisturize. However, it is worth remembering that the external use of retinol is ineffective, since the drug penetrates only into the upper layers of the epidermis.
You should immediately stop taking retinol acetate and see your doctor if you notice the following symptoms: dizziness and double vision for no reason, extensive redness and flaking of the skin, gait disorder, vomiting, bursting headache. In most cases, after timely withdrawal, side effects disappear in the near future.