Lospirin: Instructions For Use, Reviews, Analogues

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Lospirin: Instructions For Use, Reviews, Analogues
Lospirin: Instructions For Use, Reviews, Analogues

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Lospirin is an antiaggregatory agent used in cardiology. With it, you can relieve inflammation, eliminate fever and get rid of pain. It contains substances that can provoke the development of side effects, therefore, the medicine should be used strictly according to the instructions.

"Lospirin": instructions for use, reviews, analogues
"Lospirin": instructions for use, reviews, analogues

Composition and form

Lospirin is manufactured at an Indian pharmaceutical plant. The manufacturer presents to the attention of buyers the product only in tablet form. Tablets of 10 are sold in blister packs. The drug is based on acetylsalicylic acid. The auxiliary ingredients are:

  • corn starch,
  • microcrystalline cellulose,
  • stearic acid,
  • silica.
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Pharmacology

"Lospirin" refers to drugs that have an inhibitory effect on platelets. In addition, the drug stabilizes rheological blood parameters.

Acetylsalicylic acid, which is part of the drug, takes an active part in the synthesis of thromboxane. In addition, this ingredient dilates blood vessels, while increasing the fibrinolytic properties of blood plasma.

According to research, Lospirin minimizes the risk of myocardial infarction, reduces the incidence of stroke, and thins thick blood.

Pharmacokinetics

Taking acetylsalicylic acid in the composition of the drug "Lospirin", you can not worry about the gastrointestinal mucosa, since the tablets are produced in an enteric coating, that is, substances are released already in the intestine, where they are completely absorbed.

During absorption, the main component is converted to salicylic acid. Substances reach their maximum concentration in blood plasma in 10-20 minutes. The components bind to blood proteins almost completely, are quickly distributed throughout the body.

Scientists have found that salicylic acid can cross the placenta and enter breast milk. Therefore, it is undesirable to take the medicine during pregnancy and lactation.

The acid is metabolized in the liver. In the process of metabolism, it breaks down into acids and glucuronide. The half-life of acids takes 2-3 hours when taking small doses of the drug. Metabolites are excreted mainly by the kidneys.

Indications for use

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"Lospirin" is used to reduce the risk of death in patients with suspected or experienced myocardial infarction. Apply the medicine after ischemic attacks and stroke.

Cardiologists prescribe this remedy to their patients when diagnosing stable and unstable angina pectoris.

This antiaggregatory drug is used for prophylactic purposes of thrombosis, embolism, endarterectomy of the carotid artery and after coronary artery bypass grafting. If the patient has previously suffered a stroke, to prevent a secondary attack, "Lospirin" is introduced into his treatment.

Contraindications

The Indian drug "Lospirin" is not recommended to be taken if an allergy to any of the ingredients has been previously noticed.

It is worth refusing this medication for patients who suffer from asthma, have peptic ulcers or hemorrhagic diathesis.

Acetylsalicylic acid can stress the kidneys and liver, so the drug is not used for renal and hepatic insufficiency. Dangerous therapy with this drug for heart failure.

Lospirin is not compatible with all substances. Do not take it in combination with methotrexate, as they intensify each other's toxic effects. When taking the drug with anticoagulants and platelet aggregation inhibitors, the risk of bleeding increases.

If you combine the intake of acetylsalicylic acid and NSAIDs, the risk of developing gastrointestinal ulcer disease increases.

During pregnancy, the drug is possible only in the second trimester, but not on an ongoing basis, but one-time. A nursing mother who is forced to take acetylsalicylic acid should wean her baby.

Mode of application

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Lospirin tablets are taken after meals with clean water. The dose depends on the nature of the disease.

To minimize the risk of death in people with myocardial infarction, 75-300 mg of the drug is prescribed per day. The duration of treatment is 30 days. After the therapy, the doctor, after examining the patient, must decide whether to continue therapy. The same dose is set for patients who have previously suffered a stroke.

In order to prevent thromboembolism, deep vein thrombosis and myocardial infarction, patients are prescribed 75-150 mg of acetylsalicylic acid per day or 300 mg every two days.

Side effects

Lospirin, although absorbed in the intestines, can cause abdominal pain, nausea, vomiting, diarrhea, heartburn, and bloating. Sometimes doctors observe in their patients inflammation of the gastrointestinal tract mucosa, an ulcer.

Against the background of therapy, problems with the vascular system may arise, manifested in the form of bleeding, asthenia, pallor of the skin, hypoperfusion.

Sometimes, during treatment, patients' blood counts change - thrombocytopenia, anemia, hemolysis begin, so it is important to monitor blood counts during treatment.

In some cases, allergic reactions are noted in the form of rash, itching, edema, rhinitis. Problems with the kidneys, nervous system, hearing organs are possible.

Overdose

Intoxication with Lospirin is very dangerous. Signs of an overdose are:

  • dyspnea,
  • tinnitus,
  • temperature increase,
  • convulsions
  • collapse,
  • alkalosis,
  • tinnitus,
  • hyperventilation,
  • respiratory failure
  • poor kidney function.

When the above symptoms appear, vomiting or gastric lavage should be provoked. You need to stop taking medications, drink enterosorbent, laxative. In case of severe intoxication, you should seek the help of a doctor for hemodialysis.

Analogues and price

The cost of the drug "Lospirin" is about 220 rubles for 30 tablets with a dosage of 75 mg. It is very difficult to find this drug in the pharmacy network, so it is advisable to replace it with analogues.

A pharmacist can offer a foreign drug "Aspirin Cardio", which has the same main active ingredient. The price for 28 tablets with a dosage of 100 mg is 130-150 rubles.

The analogue of the drug is Acecardin, which costs 200 rubles for 50 tablets with 75 mg acetylsalicylic acid.

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Reviews about the drug "Lospirin"

Opinions about the drug "Lospirin" are very ambiguous. The drug perfectly thins the blood, prevents the formation of cholesterol plaques, is safe for the stomach, effective, and has a low cost. But it also has disadvantages, for example, it is very difficult to find it on sale, it causes side effects.

One woman was prescribed Lospirin by a cardiologist to prevent blood clots. She took it for a month at a dosage of 75 mg once a day. After the course of treatment, the blood counts became much better. There were no adverse reactions in the patient.

Another woman consulted a doctor with high hemoglobin levels. After examining the patient, the specialist decided to prescribe the drug "Acetylsalicylic acid". After several days of treatment, the woman's stomach began to hurt, and heartburn developed. Then the doctor recommended that she buy Lospirin, explaining to her that this is the same acid, but in a shell. This drug did not aggravate the gastrointestinal tract and the woman underwent the full course of treatment.

It is not worth prescribing a drug for yourself on your own, since it is not suitable for all people, and it also causes many side effects. To get rid of uncomfortable sensations, you first need to undergo an examination.

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