Pipolfen: Instructions For Use, Analogs, Release Forms

Pipolfen: Instructions For Use, Analogs, Release Forms
Pipolfen: Instructions For Use, Analogs, Release Forms

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Pipolfen is an antihistamine. The drug belongs to antiallergic drugs of the first generation, has a sedative effect.

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The medicine is a representative of the first generation of anti-allergic medicines. After use, there is a decrease in irritability, excitement. This allows you to sometimes use the drug as a sedative.

Indications

The active substance is promethazine hydrochloride. It blocks receptors from accessing the hormone histamine produced in tissues. This action reduces rashes and itching. The medication is also used as an antipyretic, antiemetic. "Pipolfen" is available in the form of tablets, ampoules. Any form of release contains 25 mg of promethazine.

To improve the absorption of pills, the composition of light dragees with a shiny surface contains talc, lactose, gelatin, starch, stearic compounds and dyes. The ampoule form of the drug looks like a clear solution of distilled water, sulfite and chloride of potassium disulfite, sodium, hydroquinone. The volume of the ampoule is 2 ml. According to the instructions, the drug is used to get rid of the manifestations of allergies.

The indications are:

  • Quincke's edema;
  • hives;
  • conjunctivitis and rhinitis;
  • hay fever;
  • pathology with itchy skin;
  • negative reaction of the immune system to the administration of serums.

Before long trips, the drug is taken as an antiemetic and to prevent dizziness. With anaphylactic shock, the drug is prescribed during rehabilitation. Also, the medication is used as a sedative before and after operations.

Pipolfen: instructions for use, analogs, release forms
Pipolfen: instructions for use, analogs, release forms

The ampoule form of release involves the use of mixtures for the rapid elimination of fever, pain relief. As an antipyretic and anti-inflammatory drug, it is recommended for severe colds accompanied by high fever.

Contraindications

Reception is limited. Prescription for shock or coma is completely excluded due to the danger of CNS depression. Do not take for apnea due to drug depression of respiratory function. Among the contraindications are poisoning with narcotic anelgesics, alcohol, sleeping pills.

The risk of suppression of vital processes is high. The medication is contraindicated in case of hypersensitivity to the active substance, lactose intolerance. If you are allergic to any phenothiazine ingredient, Pipolfen is excluded from the recommended preparations.

The combination with antidepressants of the group of MAO inhibitors is excluded. The combination can provoke a sharp drop in pressure, a violation of muscle tone. A break of at least two weeks is required between the doses of each drug group.

Lactose is included in the dragee tablets. Do not prescribe the drug in this form to babies under six years old. Injection use is permissible from the age of two months. You should not take the drug during pregnancy and lactation due to the lack of confirmation of the safety of the drug. For the period of breastfeeding, the reception is interrupted.

Pipolfen: instructions for use, analogs, release forms
Pipolfen: instructions for use, analogs, release forms

Contraindications are:

  • ulcerative diseases of the digestive system;
  • acute respiratory infections with severe cough;
  • disorders of the liver and kidneys, the process of urination;
  • Reye's syndrome;
  • inflammation of the prostate gland;
  • pulmonary diseases;
  • old age.

With such symptoms, reception is carried out only when absolutely necessary. In this case, a reduced dosage is prescribed, the doctor monitors the course of treatment. The medication has a number of side effects. Due to the sedative effect, a negative reaction to the drug on the part of the nervous system is not excluded. Probably:

  • lethargy with visual impairment;
  • dizziness;
  • confusion and disorientation;
  • apnea.

Side effects

High doses can impair muscle tone in children. There is a risk of excessive dryness of the mucous membranes, ringing and tinnitus.

With increased sensitivity to the components, dermatitis is likely, respiratory tract spasms are not excluded. Among the undesirable manifestations, cardiac arrhythmias are noted.

The number of leukocytes and platelets in the blood may decrease. Therefore, it is imperative to observe the dosage. If the permissible norm is exceeded in any form of the drug, the risk of intoxication is high. In children, it is especially severe. A clear sign of an overdose is immobile dilated pupils.

Pipolfen: instructions for use, analogs, release forms
Pipolfen: instructions for use, analogs, release forms

The drug is recommended to be stored out of the reach of children. Gastric lavage and intake of enterosorbent are necessary at the first signs of poisoning.

Then an examination by a specialist is imperative. In the hospital, they will make injections of anticonvulsants, and will conduct poisoning therapy.

Dosage

"Pipolfen" for allergic reactions take one or two pills a day. To prevent nausea, they drink one tablet per day. An hour before the start of the trip, they take it pills and take another pill eight to twelve hours later from motion sickness.

One or two pills are prescribed before the operation. As part of the mixtures, 50 mg is injected intravenously two and a half hours before the surgery. For children from six to twelve, the dosage is calculated individually, depending on weight and age.

The ampoule form allows the administration of the medication intravenously and intramuscularly. For allergies, nausea, vomiting, one ampoule is injected intramuscularly per day. Repeat as needed every four to six hours.

Before the operation, 25-50 mg is administered intramuscularly. In preparation for eye surgery and bronchoscopy, 0.15-0.3 mg per kilogram of weight is administered intravenously. For babies about two months old, an intramuscular dose of 0.5-1 mg per kilogram of weight is distributed over three to five injections per day.

Pipolfen: instructions for use, analogs, release forms
Pipolfen: instructions for use, analogs, release forms

Features of reception

Alcoholic drinks are not allowed during the course. The combination of ethanol with the drug can cause respiratory depression. The content of glucose in the blood rises. When planning testing for allergens, the drug is stopped three ducks from the start of the study.

Due to a decrease in salivation and drying of mucous membranes, the risk of developing gum disease and caries increases. Patients with a tendency to involuntary muscle contractions need to be careful during the course.

Sometimes a specialist can mistake the symptoms of the disease for a side effect of Pipolfen. So, seizures accompany the course of Reye's syndrome in children. An antihistamine medication can have a similar effect.

After the start of treatment, driving a car should be excluded for the first time. Further driving is omitted only in the absence of drowsiness.

The drug interacts with other medicines. It enhances the effect:

  • pain relievers;
  • sleeping pills;
  • tranquilizers;
  • antipsychotics;
  • anesthetics;
  • hormonal agents with prolactin;
  • anticholinergics.
Pipolfen: instructions for use, analogs, release forms
Pipolfen: instructions for use, analogs, release forms

Joint reception with drugs for epilepsy is dangerous by suppressing the work of the heart and respiratory organs.

Analogues and reviews

It is recommended to store the medication in the form of pills and injections at a temperature of fifteen to twenty-five degrees. The shelf life is five years from the date of manufacture.

The cost of tablets varies from 250 to 300 rubles for 20 pieces. Ampoules are much more expensive: 10 pieces are estimated at 640-1200 rubles. Purchase is carried out by prescription only. Self-medication is excluded.

Since the tablet form is rarely on sale, analogues of the drug are used. Promethazine is contained in Diprazine. Have a similar therapeutic effect: "Diphenhydramine", "Suprastin", "Tavegil", "Claritin". However, they all have a sedative effect.

The price of all analog drugs does not exceed 200 rubles.More modern medicines "Claritin", "Zyrtec" and "Erius" do not cause drowsiness. But they cannot be used as sedatives. Their price ranges from 250 to 950 rubles.

Reviews about Pipolfen are mostly positive. The drug worked for most of the patients. A single injection is sometimes enough to get rid of itching, rashes, inflammation.

The remedy against motion sickness has proven itself very well. Nausea and dizziness are prevented by taking the medicine one hour before the start of the trip.

Pipolfen: instructions for use, analogs, release forms
Pipolfen: instructions for use, analogs, release forms

However, there are also negative responses. Many people are not satisfied with the hypnotic effect of the drug. It is not recommended to take it during the day. With a tendency to hyper- and hypotension, pressure surges are likely. For this reason, anti-allergic medicines of the latest generation are more preferable.

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