The drug "Domperidone" has antiemetic properties. In medical practice, it is used not only by gastroenterologists, but also by oncologists and radiologists. The preparation contains a substance that stimulates the release of prolactin from the pituitary gland. Since Domperidone has a low bioavailability, it rarely disrupts the work of vital organs. One way or another, it is not shown to all people.
Domperidone is produced in the laboratory of a Russian company. The drug is presented in the form of tablets containing 10 mg of the component of the same name.
The substance domperidone enters the bloodstream quickly enough through the gastric mucosa, while not exerting a negative effect on gastric secretion. Only 15% of the drug is absorbed. The maximum concentration of the substance is reached after 1 hour. The drug is evenly distributed throughout the tissues, but its amount in the brain tissues is insignificant. Cleavage occurs in the intestines and the hematopoietic organ. Substances escape from the body through the intestines and kidneys after 7-9 hours.
A nauseating condition gives a person a lot of inconvenience - efficiency decreases, weakness appears, appetite fades away, mood worsens. It is in this case that Domperidone will help. It copes well with nausea and vomiting caused by various diseases, radiation therapy, unhealthy diet and medication.
Doctors recommend taking pills for frequent hiccups, gastrointestinal atony, flatulence, heartburn, gastralgia, belching, gastroesophageal reflux, and during X-ray examinations of the digestive tract.
"Domperidone" in no case should be introduced into therapy in the presence of gastric bleeding, intestinal obstruction, prolactin perforation of the digestive tract. Pediatricians do not use tablets for children under 5 years of age and less than 20 kg. Allergy to ingredients is an absolute contraindication.
Mode of application
Tablets containing domperidone are taken on an empty stomach (about 20 minutes before meals). With nausea and vomiting, doctors recommend drinking 20 mg of the drug three times a day. For belching, hiccups, dyspeptic symptoms, the recommended dose is 10 mg 3-4 times a day.
Although the drug was created to regulate the work of the gastrointestinal tract, sometimes patients notice a worsening of the condition. Most often this is due to an incorrectly selected dose. On the part of the nervous system, malfunctions may also occur, manifested in the form of extrapyramidal disorders. Such reactions are reversible and disappear when the drug is discontinued. But allergic reactions that may occur due to medication require antihistamine therapy.
Price and analogues
In the pharmaceutical network, you can buy Dompiridone tablets at 80 rubles for 30 pieces. You can also buy analogues that are similar in their therapeutic spectrum of action. Such drugs include Motilium, Domstal, Passages, Motonium, Motilak, Trimedat, Hexal, Omeprazole and Omez.