Cholinergic urticaria is a rare form of the disease caused by an allergy to acetylcholine produced by the body. This type of urticaria is autoimmune in nature, which is why the treatment of the disease is significantly different from the treatment of other types of allergies.
The cause of cholinergic urticaria is the increased sensitivity of the body's immune system to acetylcholine. An allergic reaction can occur as a result of constant stress, emotional and physical stress, as well as due to frequent exposure to high temperatures (sauna, steam bath, hot bath, etc.). In addition to exposure to stress factors, a person must have a genetic predisposition. It is genetics that plays a big role in the emergence of allergies.
Cholinergic urticaria can occur against the background of diseases of the gastrointestinal tract, disorders of the thyroid gland and the presence of neurocirculatory or vegetative vascular dystonia.
Urticaria symptoms appear 5-50 minutes after exposure to a stressful factor (such as taking a hot shower or emotional overload).
Allergy is characterized by the appearance on the skin of small bubbles with a diameter of 1 to 3 mm, which are pink and bright red at the edges. Rashes can occur on the neck, forearms, chest and décolleté. Hives provoke burning and itching. In some cases, against the background of the above symptoms, diarrhea, salivation, vomiting or nausea appear. The body temperature also rises.
Unlike other types of allergies, antihistamines are not prescribed for the treatment of cholinergic urticaria, since the disease occurs as a result of the body's autoimmune response to an external stimulus. The main agents used in therapy are ointments and gels. Their action is aimed at reducing the intensity of symptoms. In their composition, the preparations contain belladonna extract and the substance atropine, which can reduce itching and relieve redness. Medicines are applied 1-2 times a day and applied over the inflammation.
Diagnosis of urticaria is carried out during the examination of the patient by an allergist or dermatologist.
As an auxiliary therapy, vitamin-mineral complexes with an increased content of vitamins B and C are prescribed. This allows you to increase the immunity of the patient's body.
If the disease becomes severe, fixed-dose corticosteroid ointments and sedatives are given. The use of these drugs is possible only with the permission of the doctor after the necessary tests. For the prevention of recurrence of urticaria, alcohol, hot drinks, spicy dishes, and spices are excluded from food.
Antihistamines may only be prescribed if other allergic reactions (such as rhinitis) develop with the hives.
It is also recommended to avoid emotional stress and physical exercise that can cause increased sweating. When taking a shower, it is recommended that the water temperature be no higher than 36-38 degrees. In the presence of the disease, it is forbidden to go to the bath, sauna or take a hot bath.